Brandy Brook Avenue was originally the easternmost tenth of a mile of River Street, after its junction with Lake Flower Avenue. The name was created as part of Saranac Lake's implementation of the 911 Emergency Response System. It is named for Brandy Brook, which the street parallels as it drains Moody Pond into Lake Flower. A student at River Street School in the 1950s remembers that what is now called Brandy Brook was known to the kids as Hogwallow Creek and that a few families raised pigs in pens at the dump upstream. Brandy Brook also passed by the Saranac Lake Gas Company on Payeville Road, where it was contaminated by the waste products of the coal gasification process.
| Old Address | Post-911 Address | Building Name | Cure Evidence/Notes | |
| Starts at the end of River Street (the Lake Flower Avenue continues east | ||||
| 138 River Street | 3 Brandy Brook Avenue |
 River Street School |
||
| 145 River Street | 145 River Street (now Gauthier's Motel) | DIS | ||
| 148 River Street | 15 Brandy Brook Avenue | 1920 | ||
| 20 Brandy Brook Avenue |
 20 Brandy Brook Avenue |
1875 | ||
| 147 River Street | Kingston Cottage | DIS 1911 | ||
| 150 River Street | 25 Brandy Brook Avenue |
 150 River Street |
Original Moody homestead, General Ice Cream | |
| 151 River Street | Brandy Brook Avenue |
 Captain Thomas Cottage |
(torn down), Cure Cottages, p. 105 |
|
| 154 River Street | See 150 River Street | |||
| 155 River Street | 34 Brandy Brook Avenue | 155 River Street | ||
| 157 River Street | 38 Brandy Brook Avenue | |||
| 159 River Street | 42 Brandy Brook Avenue | 159 River Street | USC1910 | |
| 175 River Street | 167 River Street | |||
| Ends at Pine Street | ||||
