Kerns Hotel was a 162-room hotel located in the 100 block of N. Grand Ave. in Lansing, Michigan, built in 1909 by William G. Kerns. 

On December 11, 1934, a fire broke out in the Kerns Hotel, killing 32 people and injuring 44 people, including 14 firemen. It is the worst fire disaster in the history of Lansing to date.

Sources

The #KHF81 hashtag on Twitter, a commemoration of the events of the day by @MichiganHist (Mason Christensen).

Contemporary accounts

Hotel Fire in Michigan, British Movietone newsreel.

December 11, 1934. LANSING FIRE TOLL MAY REACH 50; FIVE SOLONS DIE AS HOTEL KERNS BURNS; HUNT OTHER VICTIMS. Associated Press (via GenDisasters).