The Sanitarium is a Bed & Breakfast experience in downtown San Luis Obispo. The rooms are all decorated differently and with a unique design aesthetic that caters to minimalism, cleanliness, relaxation and whimsy. Local and visiting artists can often be found in the main living area, which also serves as a musical venue on occasion.
Suzi, the owner, is also a local artist and the interior designer of the venue.
It has been featured in many publications including the New York Times: http://travel.nytimes.com/2009/05/15/travel/escapes/15Sanluis.html?_r=0
Call for a visit!