William Francis "Frank" Murphy (April 13, 1890 – July 19, 1949) was a politician and jurist from Michigan. He was named to the U.S. Supreme Court in 1940 after a political career as Governor of Michigan and Mayor of Detroit, serving also as the last Governor-General of the Philippines and then the High Commissioner of the Philippines.

Murphy was mayor of Detroit from 1930 to 1933, running as a Democrat and serving during the first years of the Great Depression.