One Manchu Prince of the Imperial Clan Court in 1839 “Those who are addicted to opium are entranced and powerless to quit, almost as if seduced by the deadly poison, until they stand like skeletons, their bodily shape totally disfigured and no better than the crippled.”

According to United Nations Office on Drugs and Crime, the East India Company sent the opium to their warehouses in the free-trade region of Canton (Guangzhou), from where Chinese smugglers would take the opium farther into China.

https://books.google.com/books?hl=zh-CN&lr=&id=CxOEDwAAQBAJ&oi=fnd&pg=PP20&dq=First+opium+war&ots=Ysd-ETLgFd&sig=UwH_7kc4gSu_-oXC_uXPgNDKg6Y#v=onepage&q=First%20opium%20war&f=false

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level of the pain scale (6).