West Virginia is recorded as the most unhappy state for the 9th year in a row. Their well-being is hindered by high levels of financial insecurity and poor physical health.  The state has the highest self-reported rates of high blood pressure, diabetes, depression, and heart attack.

https://www.usatoday.com/story/money/economy/2018/07/24/america-happiest-and-most-miserable-states-well-being/36959203/