The Melbourne CBD is laid out in a grid with the streets running NE-SW and NW-SE. Running on the NW axis the names are relatively easy to remember  - from west to east they are Spencer, King, William, Queen, Elizabeth, Swantson, Russell, Exhibition, Spring. The NE axis, from south to north, are Flinders, Collins, Bourke, Lonsdale and La Trobe. Between each of those is "Little X" immediately to the north, splitting each block up.

Block Place/Block Arcade
Bourke St, Little Bourke St, Bourke St Mall
Collins St, Little Collins St
Degraves St
Flinders St, Flinders Lane
Hosier Lane
La Trobe St
Lonsdale St, Little Lonsdale St
Royal Arcade
Russell St
Swanston St

Inner City

Bell St, Coburg
Brunswick St, Fitzroy
Hoddle St, Collingwood
Short Rd, Footscray
Victoria St, Collingwood

Here Be Dragons

Glenferrie Rd, Malvern
Fraser Ave, Upper Beaconsfield
Ramsey St, Erinsborough
Portal to London